Lateral Flow Conjugates

Lateral Flow Assays continue to be a cornerstone of rapid, point of care testing, providing quick and reliable results across healthcare, veterinary, and environmental applications. At Fleet Bioprocessing Ltd., we specialise in creating high quality antibody and antigen conjugates tailored specifically for LFA development.

Whether your assay requires gold, latex or fluorescent labels, we can deliver conjugates optimised for your chosen format. For small molecule assays, we also prepare coating conjugates, linking the target molecule to a carrier protein so it can be efficiently immobilised on the test membrane.

From early stage research to full scale production, our team can guide you through every stage of conjugate development.

Get In Touch

Why Choose Our Conjugation Service?

Cutting edge label technologies and conjugation chemistry

Flexible scale and customised solutions

Expert guidance from R&D to production

Every conjugate is optimised with your assay in mind, balancing sensitivity, matrix effects, manufacturability, and intended application.

The result is a conjugate that performs reliably in Lateral Flow devices and accelerates your assay development.

Advanced Signal Technologies:

Gold Conjugates

Carrier - Small Protein Conjugates

Fluorescent and Luminescent Dyes

Polystyrene (Latex) Particles

Biotin and Streptavidin Conjugates

Digoxigenin Conjugates

Oligonucleotide and Aptamer Conjugates

Example Projects

Hapten conjugates for lateral flow assays

For small-molecule ("hapten") assays on a lateral flow format, it is often necessary to couple the hapten to a carrier protein to enable it to be bound to the membrane. Fleet has a long and successful history of preparing such conjugates for major players in the lateral flow field, and frequently carry out routine GMP supply to support long-term manufacturing. A UK-based point-of-care diagnostics company has recently adopted Fleet's conjugates for routine use after multiple batches showed good performance in their assay.

Fluorescent lateral flow conjugates for Dutch-led collaboration

The EC-funded PreventIt project aimed to develop lateral flow tests for infectious diseases, to be used perinatally in developing countries to reduce the risk of neonatal infection. Fleet used its expertise to formulate hard-to-target glycoprotein - fluorophore conjugates for use in high-sensitivity fluorescent LFD formats.

Hormone conjugates for Global diagnostics company's lateral flow assay

Fleet had been making a hormone-protein conjugate following a well-established method that they themselves had developed and with the customer had validated; multiple batches were made over the course of >5 years. Recently, a failed batch of material caused Fleet to investigate; proactively they worked to isolate the failure to an unforeseen raw material issue. At the same time, Fleet took the opportunity to redevelop the method to improve the sensitivity of the assay and reduce the amount of critical reagents required per batch.

Fleet enable manufacture of a diagnostic reagent through improvements in process design.

Fleet’s expertise in protein modification has significantly improved the quality of a key intermediate for a UK-US lateral flow assay developer, in turn enabling the manufacture of improved reagents for coating antibody fragments.